top of page
CO2-O2-fMRI-all-over-time_edited_edited_edited_edited.jpg

Pain is a universal experience.

Our lab is interested in discovering the brain mechanisms of pain. Pain is a complex experience, and we are slowly beginning to understand the relationship between brain activity and the various pain dimensions.


We perform brain imaging research with humans and with rodent models of chronic pain. Our overall goal is to identify brain regions and circuits that change with chronic pain.

CO2-O2-fMRI-all-over-time_edited_edited_edited_edited.jpg
Screenshot 2024-07-26 at 18.15.43.png

​Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain

Many people with chronic pain suffer cognitive deficits. Using magnetic resonance imaging (MRI), Stewart et al. discover a pain-sensitive, claustrum-cortex brain circuit active in migraine patients when thinking through a task, even when not in pain. These data reveal a potential mechanism underlying the cortical network and cognitive dysfunction observed in chronic pain.

NEWS|06 MAY 2024

Contact Us

Seminowicz Pain Imaging Lab

Robarts Research Institute, University of Western Ontario

Schulich School of Medicine & Dentistry

dseminow@uwo.ca​

bottom of page